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Anti-LOXL2重组抗体|科研级 Simtuzumab ( 辛妥珠单抗 )

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Anti-LOXL2重组抗体|科研级 Simtuzumab ( 辛妥珠单抗 )
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    Catalog Number

    TKYR1290

    Alias

    科研级 Simtuzumab ( 辛妥珠单抗 ), Anti-LOXL2 Recombinant Antibody, Research Grade Simtuzumab

    Molecular Name

    Simtuzumab

    Size

    1mg, 5mg

    CAS Number

    1318075-13-6

    Isotype

    IgG4 Kappa

    Clonality

    Monoclonal

    Concentration

    1mg/ml

    Applications

    FC, IP, ELISA, Neut, FuncS

    Source

    CHO Cells

    Purity

    ≥95% as determined by SDS-PAGE

    Buffer

    Supplied in PBS, PH7.5

    Target

    LOXL2[Homo sapiens]

    Sequence

    Please contact our sales representative to learn more information about this reagents.

    Background

    Simtuzumab (INN, formerly GS 6624) is a humanized monoclonal antibody designed for the treatment of fibrosis. It binds to LOXL2 and acts as an immunomodulator. In January 2016, Gilead Sciences terminated its Phase 2 clinical study in patients with idiopathic pulmonary fibrosis (IPF) due to lack of efficacy.

    Storage

    该产品可在 2°C-8°C 下保存一个月,活性不会明显降低。在 -20°C 至 -80°C 下保存,可稳定保存十二个月。避免反复冻融,用冰袋运输。

    NOTE

    仅科研使用
    靶点背景信息
    实验方案&FAQ

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