科研级 Ieramilimab (埃拉利单抗 ), Anti-LAG3 Recombinant Antibody, Research Grade Ieramilimab
Molecular Name
Ieramilimab
Size
1mg, 5mg
CAS Number
2137049-37-5
Isotype
IgG4 Kappa
Clonality
Monoclonal
Concentration
1mg/ml
Source
CHO Cells
Purity
≥95% as determined by SDS-PAGE
Buffer
Supplied in PBS, PH7.5
Target
LAG3 [Homo sapiens]
Background
Ieramilimab (development code LAG525) is a monoclonal antibody being developed by Novartis for the treatment of cancer. The antibody targets the immune checkpoint LAG-3, which is expressed on T cells and tends to down-regulate an immune response. In a June 2015 presentation Novartis management indicated that 'dosing is imminent' for the first clinical trials of LAG525.