科研级 Clivatuzumab(克利妥珠单抗 ), Anti-CD227 Recombinant Antibody, Research Grade Clivatuzumab
Molecular Name
Clivatuzumab
Size
1mg, 5mg
CAS Number
1462876-11-4
Isotype
IgG1 Kappa
Clonality
Monoclonal
Concentration
1mg/ml
Source
CHO Cells
Purity
≥95% as determined by SDS-PAGE
Buffer
Supplied in PBS, PH7.5
Target
MUC1/CD227[Homo sapiens]
Sequence
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Background
Yttrium (90Y) clivatuzumab tetraxetan (trade name hPAM4-Cide) is a humanized monoclonal antibody-drug conjugate designed for the treatment of pancreatic cancer. The antibody part, clivatuzumab (targeted at MUC1), is conjugated with tetraxetan, a chelator for yttrium-90, a radioisotope which destroys the tumour cells.