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Anti-CD221重组抗体|科研级 Cixutumumab ( 西妥木单抗 )

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Anti-CD221重组抗体|科研级 Cixutumumab ( 西妥木单抗 )
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    Catalog Number

    TKYR1191

    Alias

    科研级 Cixutumumab ( 西妥木单抗 ), Anti-CD221 Recombinant Antibody, Research Grade Cixutumumab

    Molecular Name

    Cixutumumab

    Size

    1mg, 5mg

    CAS Number

    947687-12-9

    Isotype

    IgG1 Lambda

    Clonality

    Monoclonal

    Concentration

    1mg/ml

    Applications

    IF, IP, Neut, FuncS, ELISA, FC

    Source

    CHO Cells

    Purity

    ≥95% as determined by SDS-PAGE

    Buffer

    Supplied in PBS, PH7.5

    Target

    IGF1R/CD221[Homo sapiens]

    Sequence

    Please contact our sales representative to learn more information about this reagents.

    Background

    Cixutumumab (IMC-A12) is a human monoclonal antibody for the treatment of solid tumors. It is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor (IGF-1R) with potential antineoplastic activity. Cixutumumab selectively binds to membrane-bound IGF-1R, thereby preventing the binding of the ligand IGF-1 and subsequent activation of PI3K/AKT signaling pathway.

    Storage

    该产品可在 2°C-8°C 下保存一个月,活性不会明显降低。在 -20°C 至 -80°C 下保存,可稳定保存十二个月。避免反复冻融,用冰袋运输。

    NOTE

    仅科研使用
    靶点背景信息
    实验方案&FAQ

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